Insightly
Insightly was designed specifically with small businesses in mind. Their web-based software is intended to make running a business as simple as possible for the small business owner. They specialize in taking care of things like backups, upgrades, and security so that the business owners can focus the bigger things, like pleasing their customers. They have taken the guesswork out of customer relationship management, and have made a much higher level of efficiency attainable by small business owners around the globe. Their integrations to Google Apps, Office 365, MailChimp, and major social media sites have earned them over 800,000 users in 100 countries, and has earned them recognition as the leading small business CRM.